製品の概要

  • 製品名Anti-PYGL antibody
    PYGL 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PYGL
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to Human PYGL (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • ポジティブ・コントロール
    • Human liver

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab61013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  • 関連疾患Defects in PYGL are the cause of glycogen storage disease type 6 (GSD6) [MIM:232700]. A metabolic disorder characterized by mild to moderate hypoglycemia, mild ketosis, growth retardation, and prominent hepatomegaly. Heart and skeletal muscle are not affected.
  • 配列類似性Belongs to the glycogen phosphorylase family.
  • 翻訳後修飾Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Glycogen phosphorylase antibody
    • Glycogen phosphorylase liver antibody
    • Glycogen phosphorylase liver form antibody
    • GSD6 antibody
    • Hers disease, glycogen storage disease type VI antibody
    • liver form antibody
    • OTTHUMP00000233649 antibody
    • OTTHUMP00000233651 antibody
    • Phosphorylase glycogen liver antibody
    • Pygl antibody
    • PYGL_HUMAN antibody
    see all

Anti-PYGL antibody 画像

  • ab61013 at 10µg/ml staining formalin fixed paraffin embedded liver tissue.

Anti-PYGL antibody (ab61013) 使用論文

ab61013 has not yet been referenced specifically in any publications.

Product Wall

Unfortunately due to proprietary reasons I would not be able to provide you the exact sequence but I aligned the human sequence P06737 and the mouse sequence Q9ET01. The immunogenic peptide for antibody LS-A2283 has 80% homology between the human and t...

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