製品の概要

  • 製品名Anti-PTS antibody
    PTS 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PTS
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 1 - 111 of Human PTS (NP_000308).

  • ポジティブ・コントロール
    • 293T, H1299 and HeLa cells

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab96104 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 16 kDa.

ターゲット情報

  • 機能Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.
  • パスウェイCofactor biosynthesis; tetrahydrobiopterin biosynthesis; tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 1/3.
  • 関連疾患Defects in PTS are the cause of BH4-deficient hyperphenylalaninemia type A (HPABH4A) [MIM:261640]; also called 6-pyruvoyl-tetrahydropterin synthase deficiency (PTS deficiency) or hyperphenylalaninemia tetrahydrobiopterin-deficient due to PTS deficiency. HPABH4A is an autosomal recessive disorder characterized by depletion of the neurotransmitters dopamine and serotonin, and clinically by severe neurological symptoms unresponsive to the classic phenylalanine-low diet.
  • 配列類似性Belongs to the PTPS family.
  • 翻訳後修飾Phosphorylation of Ser-19 is required for maximal enzyme activity.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 6 pyruvoyl tetrahydrobiopterin synthase antibody
    • 6 pyruvoyl tetrahydropterin synthase antibody
    • 6 pyruvoyltetrahydropterin synthase antibody
    • 6-pyruvoyl tetrahydrobiopterin synthase antibody
    • EC 4.2.3.12 antibody
    • FLJ97081 antibody
    • OTTHUMP00000235385 antibody
    • PTP synthase antibody
    • PTPS antibody
    • PTPS_HUMAN antibody
    • PTS antibody
    see all

Anti-PTS antibody 画像

  • Anti-PTS antibody (ab96104) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size : 16 kDa

Anti-PTS antibody (ab96104) 使用論文

ab96104 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"