製品の概要

  • 製品名Anti-PTRF antibody
    PTRF 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to PTRF
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: KKAFSKEKME KTKVRTRENL EKTRLKTKEN LEKTRHTLEK RMNKLGTRLV PAERREKLKT SRDKLRKSFT PDHVVYARSK TAVYKVPPF, corresponding to amino acids 233-322 of Human PTRF

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab58019 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Plays an important role in caveolae formation and organization. Required for the sequestration of mobile caveolin into immobile caveolae. Termination of transcription by RNA polymerase I involves pausing of transcription by TTF1, and the dissociation of the transcription complex, releasing pre-rRNA and RNA polymerase I from the template. PTRF is required for dissociation of the ternary transcription complex.
    • 関連疾患Congenital generalized lipodystrophy 4
    • 配列類似性Belongs to the PTRF/SDPR family.
    • 翻訳後修飾Phosphorylated. Present in active and inactive forms. Changes in phosphorylation pattern may alter activity.
      Five truncated forms are found in the caveolae. These are thought to be the result of proteolysis and may be phosphorylation-dependent.
    • 細胞内局在Membrane > caveola. Cell membrane. Microsome. Endoplasmic reticulum. Cytoplasm > cytosol. Mitochondrion. Nucleus. Found at the surface of the caveolae. Also found in the plasma membrane, microsomal and cytosolic fractions and at a low level in the mitochondrial and nuclear fractions. Translocates to the cytoplasm from the caveolae upon insulin stimulation. CAV1 is necessary to recruit it to the cell membrane (By similarity). Co-localizes with CAV1 in lipid rafts in adipocytes.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 2310075E07Rik antibody
      • AW546441 antibody
      • Cavin 1 antibody
      • Cavin antibody
      • Cavin-1 antibody
      • CAVIN1 antibody
      • CGL4 antibody
      • FKSG13 antibody
      • FLJ90031 antibody
      • MGC118550 antibody
      • OTTMUSP00000002049 antibody
      • Polymerase I and transcript release factor antibody
      • Ptrf antibody
      • PTRF_HUMAN antibody
      • RNA polymerase I and transcript release factor antibody
      • RP23-279L23.6 antibody
      • TTF I interacting peptide 12 antibody
      see all

    Anti-PTRF antibody 画像

    • PTRF antibody (ab58019) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human pancreas.

    Anti-PTRF antibody (ab58019) 使用論文

    ab58019 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab58019.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"