製品の概要

  • 製品名Anti-PSMA7 antibody
    PSMA7 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PSMA7
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Zebrafish
  • 免疫原

    Recombinant fragment corresponding to Human PSMA7 aa 10-217.
    Database link: O14818

  • ポジティブ・コントロール
    • WB: 293T, A431, H1299, HeLa, HepG2, MOLT4 and Raji cell lysates IHC-P: CL15 xenograft

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab97564 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 28 kDa.
IHC-P 1/100 - 1/500.

ターゲット情報

  • 機能The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
  • 配列類似性Belongs to the peptidase T1A family.
  • 翻訳後修飾Phosphorylation by ABL1 or ABL2 leads to an inhibition of proteasomal activity and cell cycle transition blocks.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C6 antibody
    • HSPC antibody
    • MGC3755 antibody
    • OTTHUMP00000031449 antibody
    • OTTHUMP00000031450 antibody
    • OTTHUMP00000031453 antibody
    • Proteasome (prosome macropain) subunit alpha type 7 antibody
    • Proteasome alpha 7 subunit antibody
    • Proteasome subunit alpha 4 antibody
    • Proteasome subunit alpha type 7 antibody
    • Proteasome subunit alpha type-7 antibody
    • Proteasome subunit RC6 1 antibody
    • Proteasome subunit RC6-1 antibody
    • Proteasome subunit XAPC7 antibody
    • PSA7_HUMAN antibody
    • PSMA 7 antibody
    • PSMA7 antibody
    • RC6 1 antibody
    • XAPC7 antibody
    see all

Anti-PSMA7 antibody 画像

  • All lanes : Anti-PSMA7 antibody (ab97564) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : H1299 whole cell lysate
    Lane 3 : HeLa whole cell lysate
    Lane 4 : HepG2 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 28 kDa
  • ab97564, at a 1/100 dilution, staining PSMA7 in a paraffin-embedded CL15 xenograft by Immunohistochemical analysis.

Anti-PSMA7 antibody (ab97564) 使用論文

ab97564 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"