製品の概要

  • 製品名Anti-PSCA antibody
    PSCA 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PSCA
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (extracellular).

  • ポジティブ・コントロール
    • Bladder carcinoma and Prostate carcinoma.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: 1% BSA, 10mM PBS, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab15168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/75. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

ターゲット情報

  • 関連性PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
  • 細胞内局在Cell membrane; Lipid-anchor, GPI-anchor.
  • 参照データベース
  • 別名
    • PRO 232 antibody
    • PRO232 antibody
    • Prostate stem cell antigen antibody

Anti-PSCA antibody 画像

  • ab15168 staining PSCA in human breast carcinoma by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).

Anti-PSCA antibody (ab15168) 使用論文

This product has been referenced in:
  • Smith C  et al. Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia: a case-control and immunohistochemical study. BMC Res Notes 5:371 (2012). IHC-P ; Human . Read more (PubMed: 22824379) »

See 1 Publication for this product

Product Wall

Antigen retrieval protocol: 1. Put tissue slides in 1X citrate buffer pH 6.0(we usually use 300ml container with 250ml buffer). 2. Microwave at high power for several minutes(one container for 2 and half minutes, two containers for 4 and half minutes...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"