Anti-Protein Phosphatase 1 beta 抗体 [AF9B12] (ab80942)


  • 製品名
    Anti-Protein Phosphatase 1 beta antibody [AF9B12]
    Protein Phosphatase 1 beta 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [AF9B12] to Protein Phosphatase 1 beta
  • 特異性
    ab80942 does not cross react with PPP1C alpha and PPP1C gamma.
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Recombinant human Protein Phosphatase 1 beta purified from E.coli (His-Protein Phosphatase 1 beta)

  • ポジティブ・コントロール
    • Jurkat, MOLT4, HT29, A431, SKNSH, PC12 and NIH3T3 cell lysates.



Our Abpromise guarantee covers the use of ab80942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).


  • 機能
    Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).
  • 配列類似性
    Belongs to the PPP phosphatase family. PP-1 subfamily.
  • 細胞内局在
    Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus. Highly mobile in cells and can be relocalized through interaction with targeting subunits. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MGC3672 antibody
    • PP 1B antibody
    • PP-1B antibody
    • PP1B antibody
    • PP1B_HUMAN antibody
    • PP1beta antibody
    • PPP1CB antibody
    • PPP1CD antibody
    • Protein phosphatase 1 beta antibody
    • Protein phosphatase 1 catalytic subunit beta isoform antibody
    • Protein phosphatase 1 delta antibody
    • Protein phosphatase 1, catalytic subunit, beta isozyme antibody
    • Protein phosphatase 1, catalytic subunit, delta isoform antibody
    • Serine threonine protein phosphatase PP1 beta catalytic subunit antibody
    • Serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody
    see all

Anti-Protein Phosphatase 1 beta antibody [AF9B12] 画像

  • All lanes : Anti-Protein Phosphatase 1 beta antibody [AF9B12] (ab80942)

    Lane 1 : Jurkat cell lysate
    Lane 2 : MOLT4 cell lysate
    Lane 3 : HT29 cell lysate
    Lane 4 : A431 cell lysate
    Lane 5 : SKNSH cell lysate
    Lane 6 : PC12 cell lysate
    Lane 7 : NIH3T3 cell lysate

    Predicted band size : 37 kDa
    Observed band size : 37 kDa


Anti-Protein Phosphatase 1 beta antibody [AF9B12] (ab80942) 使用論文

ab80942 has not yet been referenced specifically in any publications.

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