製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • アクセッション番号P28065
    • 配列RVILGN/DELPKFYDE
    • 領域207 to 220

関連製品

特性

Our Abpromise guarantee covers the use of ab4944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態Liquid
  • 備考


    These peptides may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and mouse proteasome 20S LMP2, catalog ab4944. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

関連情報

  • 別名
    • Beta1i
    • Large multifunctional peptidase 2
    • Large multifunctional protease 2
    • LMP 2
    • LMP2
    • Low molecular mass protein 2
    • Macropain chain 7
    • MGC70470
    • Multicatalytic endopeptidase complex chain 7
    • OTTHUMP00000062982
    • Proteasome (prosome macropain) subunit beta type 9
    • proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
    • Proteasome beta 9 subunit
    • Proteasome catalytic subunit 1i
    • Proteasome chain 7
    • Proteasome related gene 2
    • Proteasome subunit beta 6i
    • Proteasome subunit beta type 9
    • Proteasome subunit beta type-9
    • Proteasome subunit beta-1i
    • PSB9_HUMAN
    • PSMB 9
    • PSMB6i
    • PSMB9
    • Really interesting new gene 12 protein
    • RING 12
    • RING12
    • RING12 protein
    see all
  • 機能The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues.
  • 配列類似性Belongs to the peptidase T1B family.
  • 発生段階Highly expressed in immature dendritic cells (at protein level).
  • 翻訳後修飾Autocleaved. The resulting N-terminal Thr residue of the mature subunit is responsible for the nucleophile proteolytic activity.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt

Proteasome 20S LMP2 peptide (ab4944) 使用論文

ab4944 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"