Rabbit polyclonal to Proteasome 19S S5A
Recombinant full length protein (Saccharomyces cerevisiae)
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/5000. Detects a band of approximately 58 kDa (predicted molecular weight: 29 kDa).
Binds and presumably selects ubiquitin-conjugates for destruction. Displays selectivity for longer polyubiquitin chains. Modulates intestinal fluid secretion.
Belongs to the proteasome subunit S5A family.
Contains 2 UIM (ubiquitin-interacting motif) repeats.
Contains 1 VWFA domain.
The 2 UIM motifs are involved in the binding to a multi-ubiquitin chain in a cooperative way.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
- 26S protease subunit S5a antibody
- 26S proteasome non ATPase regulatory subunit 4 antibody
- 26S proteasome non-ATPase regulatory subunit 4 antibody
has not yet been referenced specifically in any publications.
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