製品の概要

  • 製品名
    Anti-Proteasome 19S S5A antibody
    Proteasome 19S S5A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Proteasome 19S S5A
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Drosophila melanogaster
  • 免疫原

    Full length protein (Drosophila melanogaster).

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: None
    Constituents: Whole serum
  • 精製度
    Whole antiserum
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab18512 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 41 kDa.

ターゲット情報

  • 機能
    Binds and presumably selects ubiquitin-conjugates for destruction. Displays selectivity for longer polyubiquitin chains. Modulates intestinal fluid secretion.
  • 配列類似性
    Belongs to the proteasome subunit S5A family.
    Contains 2 UIM (ubiquitin-interacting motif) repeats.
    Contains 1 VWFA domain.
  • ドメイン
    The 2 UIM motifs are involved in the binding to a multi-ubiquitin chain in a cooperative way.
  • 翻訳後修飾
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt
  • 参照データベース
    • 別名
      • 26S protease subunit S5a antibody
      • 26S proteasome non ATPase regulatory subunit 4 antibody
      • 26S proteasome non-ATPase regulatory subunit 4 antibody
      • 26S proteasome regulatory subunit rpn10 antibody
      • 26S proteasome regulatory subunit S5A antibody
      • AF 1 antibody
      • AF antibody
      • AF1 antibody
      • Angiocidin antibody
      • Antisecretory factor 1 antibody
      • ASF antibody
      • DS5a antibody
      • MCB 1 antibody
      • MCB1 antibody
      • Multiubiquitin chain binding protein antibody
      • Multiubiquitin chain-binding protein antibody
      • OTTHUMP00000059963 antibody
      • Prosome macropain antibody
      • Proteasome (prosome macropain) 26S subunit non ATPase 4 antibody
      • Proteasome 26S non ATPase subunit 4 antibody
      • Proteasome 26S subunit non ATPase 4 antibody
      • PSMD 4 antibody
      • Psmd4 antibody
      • PSMD4_HUMAN antibody
      • pUB R5 antibody
      • pUBR5 antibody
      • Rpn 10 antibody
      • Rpn10 antibody
      • RPN10 homolog antibody
      • S5A antibody
      • S5a/antisecretory factor protein antibody
      see all

    画像

    • Western blot - Anti-Proteasome 19S S5A antibody (ab18512)
      Western blot - Anti-Proteasome 19S S5A antibody (ab18512)
      Crude Drosophila extract. Secondary antibody: rabbit polyclonal 1:5000. Please note: Drosophila S5a has an actual mass of 42.6 kDa, however, on the gel it runs at an apparent 54 kDa band.

    プロトコール

    参考文献

    This product has been referenced in:
    • Vernace VA  et al. Aging and regulated protein degradation: who has the UPPer hand? Aging Cell 6:599-606 (2007). WB ; Drosophila melanogaster . Read more (PubMed: 17681036) »

    See 1 Publication for this product

    ab18512 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    レビューと Q&A

    レビューを送る 質問を送る

    1 Review or Q&A

    10
    Votes: Highest First


    I am looking for an proteasome antibody that can work in immunostaining of
    drosophila proteasome 19s. And I came across the product ab18512 in your
    company. It gives a nice signal in the western blot, but no evidence about
    the immun...

    Read More

    Thank you very much for your interest in ab18512.

    To our knowledge, ab18512 has not been tested in ICC/IF. We do not have trial sizes of our antibodies because we have over 90,000 products in our automated freezers. Therefore, I can offer a ...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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