Major prostanoid; important precursor in eicosanoid synthesis
Major prostanoid; important precursor in eicosanoid synthesis. Formed following catalysis of arachidonic acid (AA) by COX and is subsequently converted by cell-specific synthases to form biologically active PGs and thromboxane.
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Lin L et al. Expression of prostaglandin H2-mediated mechanism of vascular contraction in hypertensive rats. Relation to lipoxygenase and prostacyclin synthase activities. Circ Res74:197-205 (1994).
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Gorman RR et al. Inhibition of basal and hormone-stimulated adenylate cyclase in adipocyte ghosts by the prostaglandin endoperoxide prostaglandin H2. J Biol Chem250:6460-3 (1975).
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