Anti-Prostaglandin dehydrogenase 1 抗体 (ab26076)

製品の概要

  • 製品名Anti-Prostaglandin dehydrogenase 1 antibody
    Prostaglandin dehydrogenase 1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Prostaglandin dehydrogenase 1
  • 特異性ab26076 recognises Prostaglandin dehydrogenase 1.
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    C DYDTTPFQAKTQ

    , corresponding to C terminal amino acids 255-266 of Human Prostaglandin dehydrogenase 1

  • ポジティブ・コントロール
    • Human duodenum lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: Tris saline, 0.5% BSA. pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab26076 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/128000.
WB Use a concentration of 0.1 - 1 µg/ml. Detects a band of approximately 26, 50 kDa (predicted molecular weight: 30 kDa).

ターゲット情報

  • 機能Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
  • 組織特異性Detected in colon epithelium (at protein level).
  • 関連疾患Defects in HPGD are the cause of primary hypertrophic osteoathropathy autosomal recessive (PHOAR) [MIM:259100]; also known as pachydermoperiostosis autosomal recessive. Primary hypertrophic osteoarthropathy is characterized by digital clubbing, osterarthropathy, variable features of pachydermia, delayed closure of the fontanels, and congenital heart disease.
    Defects in HPGD are the cause of cranioosteoarthropathy (COA) [MIM:259100]. Clinical features include infantile onset of swelling of the joints, digital clubbing, hyperhidrosis, delayed closure of the fontanels, periostosis, and variable patent ductus arteriosus. Pachydermia is not a prominent feature.
    Defects in HPGD are a cause of isolated congenital nail clubbing (ICNC) [MIM:119900]; also called clubbing of digits or hereditary acropachy. ICNC is a rare genodermatosis characterized by enlargement of the nail plate and terminal segments of the fingers and toes, resulting from proliferation of the connective tissues between the nail matrix and the distal phalanx. It is usually symmetrical and bilateral (in some cases unilateral). In nail clubbing usually the distal end of the nail matrix is relatively high compared to the proximal end, while the nail plate is complete but its dimensions and diameter more or less vary in comparison to normal. There may be different fingers and toes involved to varying degrees. Some fingers or toes are spared, but the thumbs are almost always involved.
  • 配列類似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 15 hydroxyprostaglandin dehydrogenase [NAD+] antibody
    • 15 PGDH antibody
    • 15-hydroxyprostaglandin dehydrogenase [NAD+] antibody
    • 15-PGDH antibody
    • 15PGDH antibody
    • Hpgd antibody
    • Hydroxyprostaglandin dehydrogenase 15 (NAD) antibody
    • NAD+ dependent 15 hydroxyprostaglandin dehydrogenase antibody
    • OTTHUMP00000218960 antibody
    • OTTHUMP00000219016 antibody
    • OTTHUMP00000219018 antibody
    • PGDH antibody
    • PGDH_HUMAN antibody
    • PGDH1 antibody
    • PHOAR1 antibody
    • Prostaglandin dehydrogenase 1 antibody
    • SDR36C1 antibody
    • Short chain dehydrogenase/reductase family 36C member 1 antibody
    see all

Anti-Prostaglandin dehydrogenase 1 antibody 画像

  • Anti-Prostaglandin dehydrogenase 1 antibody (ab26076) at 0.1 µg/ml + Human duodenal lysate (35ug) at 35 µg
    Developed using the ECL technique

    Predicted band size : 30 kDa
    Observed band size : 26 & 50 kDa (why is the actual band size different from the predicted?)

Anti-Prostaglandin dehydrogenase 1 antibody (ab26076) 使用論文

ab26076 has not yet been referenced specifically in any publications.

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