Anti-Prostaglandin D Synthase (Lipocalin) 抗体 (ab61866)


  • 製品名Anti-Prostaglandin D Synthase (Lipocalin) antibody
    Prostaglandin D Synthase (Lipocalin) 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Prostaglandin D Synthase (Lipocalin)
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Sheep, Rabbit, Horse, Cow, Cat, Dog, Monkey
  • 免疫原

    Synthetic peptide corresponding to Human Prostaglandin D Synthase (Lipocalin) aa 120-190 (internal sequence).

  • ポジティブ・コントロール
    • Human brain lysate.


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: 30% Glycerol, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野


Our Abpromise guarantee covers the use of ab61866 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 2 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 21 kDa).


  • 機能Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.
  • 組織特異性Abundant in the brain and CNS, where it is expressed in tissues of the blood-brain barrier and secreted into the cerebro-spinal fluid. Abundantly expressed in the heart. In the male reproductive system, it is expressed in the testis, epididymis and prostate, and is secreted into the seminal fluid. Expressed in the eye and secreted into the aqueous humor. Lower levels detected in various tissue fluids such as serum, normal urine, ascitic fluid and tear fluid. Also found in a number of other organs including ovary, fimbriae of the fallopian tubes, kidney, leukocytes.
  • 配列類似性Belongs to the calycin superfamily. Lipocalin family.
  • 発生段階Expression in the amniotic fluid increases dramatically during weeks 12 to 25 of pregnancy. Levels decrease slowly after 25 weeks.
  • ドメインForms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
  • 翻訳後修飾Both N-glycosylation recognition sites are almost quantitatively occupied by N-glycans of the biantennary complex type, with a considerable proportion of structures bearing a bisecting GlcNAc. Agalacto structure as well as sialylated and nonsialylated oligosaccharides bearing alpha2-3- and/or alpha2-6-linked NeuNAc are present.
  • 細胞内局在Rough endoplasmic reticulum. Nucleus membrane. Golgi apparatus. Cytoplasm > perinuclear region. Secreted. Detected on rough endoplasmic reticulum of arachnoid and menigioma cells. Localized to the nuclear envelope, Golgi apparatus, secretory vesicles and spherical cytoplasmic structures in arachnoid trabecular cells, and to circular cytoplasmic structures in meningeal macrophages and perivascular microglial cells. In oligodendrocytes, localized to the rough endoplasmic reticulum and nuclear envelope. In retinal pigment epithelial cells, localized to distinct cytoplasmic domains including the perinuclear region. Also secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Beta trace protein antibody
    • Beta-trace protein antibody
    • Cerebrin 28 antibody
    • Cerebrin-28 antibody
    • glutathione independent PGD synthase antibody
    • Glutathione independent PGD synthetase antibody
    • Glutathione-independent PGD synthase antibody
    • L PGDS antibody
    • Lipocalin type prostaglandin D synthase antibody
    • Lipocalin-type prostaglandin-D synthase antibody
    • LPGDS antibody
    • PDS antibody
    • PGD2 antibody
    • PGD2 synthase antibody
    • PGDS antibody
    • PGDS2 antibody
    • prostaglandin D synthase antibody
    • prostaglandin D2 synthase (21 kDa, brain) antibody
    • prostaglandin D2 synthase (brain) antibody
    • prostaglandin D2 synthase 21kDa (brain) antibody
    • Prostaglandin D2 synthase antibody
    • prostaglandin H2 D isomerase antibody
    • Prostaglandin-D2 synthase antibody
    • Prostaglandin-H2 D-isomerase antibody
    • PTGDS antibody
    • PTGDS_HUMAN antibody
    • RP23-47P18.11-006 antibody
    see all

Anti-Prostaglandin D Synthase (Lipocalin) antibody 画像

  • Lane 1 : Anti-Prostaglandin D Synthase (Lipocalin) antibody (ab61866) at 0.5 µg/ml
    Lane 2 : Anti-Prostaglandin D Synthase (Lipocalin) antibody (ab61866) at 2 µg/ml

    Lane 1 : Human brain lysate
    Lane 2 : Human brain lysate

    Predicted band size : 21 kDa
    Observed band size : 28 kDa (why is the actual band size different from the predicted?)

Anti-Prostaglandin D Synthase (Lipocalin) antibody (ab61866) 使用論文

ab61866 has not yet been referenced specifically in any publications.

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