Anti-Prostaglandin D Synthase (hematopoietic) 抗体 (ab89709)


  • 製品名Anti-Prostaglandin D Synthase (hematopoietic) antibody
    Prostaglandin D Synthase (hematopoietic) 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Prostaglandin D Synthase (hematopoietic)
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 36 - 85 (QADWPEIKST LPFGKIPILE VDGLTLHQSL AIARYLTKNT DLAGNTEMEQ) of Human Prostaglandin D Synthase (hematopoietic) (NP_055300).

  • ポジティブ・コントロール
    • Human fetal spleen lysate.


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野


Our Abpromise guarantee covers the use of ab89709 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 4 - 8 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 23 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • 機能Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
  • 組織特異性Expressed in a number of megakaryocytic cell lines but not in platelets. Highly expressed in adipose tissue, macrophages and placenta. Also expressed at lower levels in lung, heart, lymph nodes, appendix, bone marrow and fetal liver.
  • 配列類似性Belongs to the GST superfamily. Sigma family.
    Contains 1 GST C-terminal domain.
    Contains 1 GST N-terminal domain.
  • 発生段階Highest levels in immature megakaryocytic cells. Disappears after final differentiation to platelets.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cerebrin 28 antibody
    • Glutathione dependent PGD synthetase antibody
    • Glutathione S-transferase antibody
    • Glutathione-dependent PGD synthase antibody
    • Glutathione-requiring prostaglandin D synthase antibody
    • GST class-sigma antibody
    • H PGDS antibody
    • H-PGDS antibody
    • Haematopoietic prostaglandin D synthase antibody
    • Haematopoietic prostaglandin D2 synthase antibody
    • Hematopoietic prostaglandin D synthase antibody
    • Hpgds antibody
    • HPGDS_HUMAN antibody
    • Prostaglandin D synthase antibody
    • Prostaglandin D2 synthase hematopoietic antibody
    • Prostaglandin H2 D isomerase antibody
    • Prostaglandin-H2 D-isomerase antibody
    • PTGDS2 antibody
    see all

Anti-Prostaglandin D Synthase (hematopoietic) antibody 画像

  • Anti-Prostaglandin D Synthase (hematopoietic) antibody (ab89709) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal spleen lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 23 kDa
    Gel concentration: 12%
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung tissue labelling Prostaglandin D Synthase with ab89709 at 4-8µg/ml.

Anti-Prostaglandin D Synthase (hematopoietic) antibody (ab89709) 使用論文

This product has been referenced in:
  • Feng X  et al. Eosinophil production of prostaglandin D2 in patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol 138:1089-1097.e3 (2016). Read more (PubMed: 27423494) »

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