Anti-Properdin/PFC 抗体 [10-18] (ab58984)
Key features and details
- Mouse monoclonal [10-18] to Properdin/PFC
- Suitable for: ELISA, IHC-Fr, Functional Studies
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-Properdin/PFC antibody [10-18]
Properdin/PFC 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [10-18] to Properdin/PFC -
由来種
Mouse -
アプリケーション
適用あり: ELISA, IHC-Fr, Functional Studiesmore details -
種交差性
交差種: Human -
免疫原
Full length native protein (purified) corresponding to Human Properdin/PFC.
Database link: P27918 -
ポジティブ・コントロール
- Histology positive control tissue: Kidney from post streptococcal glomerulonephritis patients.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 8.20
Preservative: 0.1% Sodium azide
Constituent: 99% Borate buffered saline -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
10-18 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab58984の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ELISA | ||
IHC-Fr | ||
Functional Studies |
特記事項 |
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FuncS: Use at an assay dependent dilution.
Note: This antibody inhibits the function of Properdin. Removal of sodium azide is recommended prior to use in functional assays
IHC-Fr: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. -
関連疾患
Defects in CFP are the cause of properdin deficiency (PFD) [MIM:312060]. PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III). -
配列類似性
Contains 6 TSP type-1 domains. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 5199 Human
- Omim: 300383 Human
- SwissProt: P27918 Human
- Unigene: 53155 Human
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別名
- BFD antibody
- CFP antibody
- Complement factor P antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab58984 は論文での使用が確認できていません。