製品の概要

  • 製品名Anti-Prokineticin 1 antibody
    Prokineticin 1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Prokineticin 1
  • 特異性The polyclonal antibody reacts specificly with human prokinectin 1.
  • アプリケーション適用あり: WB, Flow Cyt, IHC-P, IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide derived from N terminal region of Human prokinectin 1

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: None
    Constituents: Whole serum
  • 精製度Whole antiserum
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab42802 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/200. Predicted molecular weight: 12 kDa.Can be blocked with Prokineticin 1 peptide (ab206194).
Flow Cyt 1/100. ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
IHC-P 1/50.
IHC-Fr 1/50.

ターゲット情報

  • 機能Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.
  • 組織特異性Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta.
  • 配列類似性Belongs to the AVIT (prokineticin) family.
  • 発生段階In adult testis, is strongly expressed only in Leydig cells. In testicular tumors, expressed specifically in Leydig cell tumors (at protein level). Expressed from 14 weeks until birth in fetal testis.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Black mamba toxin related protein antibody
    • EG VEGF antibody
    • EG-VEGF antibody
    • EGVEGF antibody
    • Endocrine-gland-derived vascular endothelial growth factor antibody
    • Mambakine antibody
    • PK1 antibody
    • PRK1 antibody
    • PROK1 antibody
    • PROK1_HUMAN antibody
    • Prokineticin-1 antibody
    see all

Anti-Prokineticin 1 antibody 画像

  • ab42802 at 0.33 µg/ml staining Prokinectin 1 in tissue of chorionic villi at 9 weeks of gestation. Staining can be observed in Cytotrophoblast (Cyt), Hobfauer cells (Ho), Extravillous trophoblast (Evt) and Syncytiotrophoblast (St). Negative control with preimmune serum shows no staining. Counterstaining performed with haematoxylin.

Anti-Prokineticin 1 antibody (ab42802) 使用論文

ab42802 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"