Anti-proCathepsin D 抗体 [AF4G5] (ab119710)

製品の概要

  • 製品名Anti-proCathepsin D antibody [AF4G5]
    proCathepsin D 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [AF4G5] to proCathepsin D
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Recombinant Human proCathepsin D purified from E.coli with His tag.

  • ポジティブ・コントロール
    • MCF7, HepG2 and SK-BR3 cell lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab119710 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/2000. Predicted molecular weight: 45 kDa.

ターゲット情報

  • 機能Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
  • 関連疾患Defects in CTSD are the cause of neuronal ceroid lipofuscinosis type 10 (CLN10) [MIM:610127]; also known as neuronal ceroid lipofuscinosis due to cathepsin D deficiency. A form of neuronal ceroid lipofuscinosis with onset at birth or early childhood. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material, and clinically by seizures, dementia, visual loss, and/or cerebral atrophy.
  • 配列類似性Belongs to the peptidase A1 family.
  • 細胞内局在Lysosome. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CATD_HUMAN antibody
    • cathepsin D (lysosomal aspartyl protease) antibody
    • Cathepsin D antibody
    • Cathepsin D heavy chain antibody
    • Ceroid-lipofuscinosis, neuronal 10 antibody
    • CLN10 antibody
    • CPSD antibody
    • ctsd antibody
    • EC 3.4.23 antibody
    • EC 3.4.23.5 antibody
    • Lysosomal aspartyl peptidase antibody
    • Lysosomal aspartyl protease antibody
    • MGC2311 antibody
    • OTTHUMP00000042282 antibody
    • OTTHUMP00000196039 antibody
    • OTTHUMP00000198692 antibody
    see all

Anti-proCathepsin D antibody [AF4G5] 画像

  • All lanes : Anti-proCathepsin D antibody [AF4G5] (ab119710) at 1/500 dilution

    Lane 1 : MCF7 cell lysate
    Lane 2 : HepG2 cell lysate
    Lane 3 : SK-BR3 cell lysate


    Predicted band size : 45 kDa

Anti-proCathepsin D antibody [AF4G5] (ab119710) 使用論文

ab119710 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"