Anti-Procalcitonin 抗体 [42] (HRP) (ab24454)

製品の概要

  • 製品名Anti-Procalcitonin antibody [42] (HRP)
    Procalcitonin 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [42] to Procalcitonin (HRP)
  • 標識HRP
  • 特異性Specific for N-terminal fragment.
  • アプリケーション適用あり: Sandwich ELISA, ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment (Human)

  • エピトープaa 21-40

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.05% Proclin
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • クローン名42
  • ミエローマSp2/0
  • アイソタイプIgG2a
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab24454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Sandwich ELISA Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [16B5] to Calcitonin (ab11493). Can be used as Detection antibody.
ELISA Use at an assay dependent dilution. Can be paired for ELISA with Mouse monoclonal [16B5] to Calcitonin (ab11493).
WB Use at an assay dependent dilution. Predicted molecular weight: 15 kDa.

ターゲット情報

  • 関連性Procalcitonin (PCT) is a 116 amino acid residue peptide with molecular weight of about 13 kDa. PCT itself has no known hormonal activity. PCT belongs to a group of related proteins including calcitonin gene-related peptides I and II, amylin, adrenomodulin and calcitonin (CAPA peptide family). PCT, like other peptides of CAPA family, appears from the common precursor pre-procalcitonin consisting of 141 amino acids by removal of 25 amino acids from the N-terminus. PCT undergoes successive cleavages to form three molecules: N-terminal fragment (55 a.a.), calcitonin (32 a.a.) and katacalcin (21 a.a.). Under normal metabolic conditions, PCT is only present in the C cells of the thyroid gland. In bacterial infection and sepsis, however, intact PCT is found in the blood and, more importantly, its level is related to the severity of bacterial sepsis. Today, PCT is considered to be one of the earliest and most specific markers of sepsis.
  • 細胞内局在Secreted
  • 参照データベース
  • 別名
    • CALC1 antibody
    • CALCA antibody
    • calcitonin related polypeptide alpha antibody
    • CGRP antibody
    • CGRP1 antibody
    • CT antibody
    • katacalcin antibody
    • KC antibody
    see all

Anti-Procalcitonin antibody [42] (HRP) (ab24454) 使用論文

ab24454 has not yet been referenced specifically in any publications.

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The procalcitonin antibody ab24454 has not been tested for reactivity with canine procalcitonin but an alignment of the immunogen sequence with the canine protein's amino acid sequence shows 71% identity. The for...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"