製品の概要
- 製品名Anti-proBNP antibody
proBNP 一次抗体 製品一覧 - 製品の詳細Rabbit polyclonal to proBNP
- 特異性ab32842 recognises Pro-Brain Natriuretic Peptide.
- アプリケーション適用あり: WB, IPmore details
- 種交差性交差種: Human
- 免疫原
Synthetic peptide corresponding to Human proBNP aa 104-123.
Sequence:PKMVQGS GCFGRKMDRI SSS
製品の特性
- 製品の状態Liquid
- 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- バッファーPreservative: 0.02% Sodium Azide
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Concentration information loading... - 精製度Protein G purified
- ポリ/モノポリクローナル
- アイソタイプIgG
- 研究分野
関連製品
- Compatible Secondaries
- Positive Controls
アプリケーション
Our Abpromise guarantee covers the use of ab32842 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | 1/500. Predicted molecular weight: 16-18 kDa. | |
| IP | 1/200. (1µl/250µg protein extract) |
ターゲット情報
- 機能Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
- 組織特異性Brain and also in atria, but at much lower levels than ANP.
- 配列類似性Belongs to the natriuretic peptide family.
- 細胞内局在Secreted.
- Information by UniProt
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参照データベース
- Entrez Gene: 4879 Human
- Omim: 600295 Human
- SwissProt: P16860 Human
- Unigene: 219140 Human
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別名
- ANFB_HUMAN antibody
- BNP antibody
- BNP(1-32) antibody
see all
Anti-proBNP antibody (ab32842) 使用論文
This product has been referenced in:
- Li L et al. Role of brain serotonin dysfunction in the pathophysiology of congestive heart failure. J Mol Cell Cardiol : (2012). WB ; Mouse . Read more (PubMed: 22921782) »
- Zhan DY et al. Therapeutic effect of {beta}-adrenoceptor blockers using a mouse model of dilated cardiomyopathy with a troponin mutation. Cardiovasc Res 84:64-71 (2009). Read more (PubMed: 19477965) »
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"