製品の概要

  • 製品名
    Anti-proBNP antibody
    proBNP 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to proBNP
  • 由来種
    Rabbit
  • 特異性
    ab32842 recognises Pro-Brain Natriuretic Peptide.
  • アプリケーション
    適用あり: WB, IPmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to Human proBNP aa 104-123.
    Sequence:

    PKMVQGS GCFGRKMDRI SSS

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab32842 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500. Predicted molecular weight: 16-18 kDa.
IP 1/200. (1µl/250µg protein extract)

ターゲット情報

  • 機能
    Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • 組織特異性
    Brain and also in atria, but at much lower levels than ANP.
  • 配列類似性
    Belongs to the natriuretic peptide family.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
    • 別名
      • ANFB_HUMAN antibody
      • BNP antibody
      • BNP(1-32) antibody
      • BNP(5-29) antibody
      • BNP-32 antibody
      • Brain type natriuretic peptide antibody
      • Gamma brain natriuretic peptide antibody
      • Gamma-brain natriuretic peptide antibody
      • Natriuretic peptide precursor B antibody
      • nppb antibody
      • NT proBNP antibody
      see all

    参考文献

    This product has been referenced in:
    • Du CK  et al. Survival benefit of ghrelin in the heart failure due to dilated cardiomyopathy. Pharmacol Res Perspect 2:e00064 (2014). Read more (PubMed: 25505608) »
    • Li L  et al. Role of brain serotonin dysfunction in the pathophysiology of congestive heart failure. J Mol Cell Cardiol : (2012). WB ; Mouse . Read more (PubMed: 22921782) »

    See all 3 Publications for this product

    ab32842 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

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