製品の概要

  • 製品名Anti-proBNP antibody [15F11]
    proBNP 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [15F11] to proBNP
  • アプリケーション適用あり: ELISA, WB, IP, Sandwich ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    ETSGLQEQRNHLQGK

    , corresponding to amino acids 13 - 27 of Human proBNP.

  • 特記事項Immunoglobulin concentrations vary from batch to batch. Please contact technical services for the latest information.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab13115 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Detects a band of approximately 13 kDa.
IP Use at an assay dependent concentration. PubMed: 21482747
Sandwich ELISA Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [24E11] to proBNP (HRP) (ab13123). Can be used as capture antibody in conjunction with recommended pair. Recognises the antigen in blood of patients with heart faliure, unstable angina and myocardial infarction.

ターゲット情報

  • 機能Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • 組織特異性Brain and also in atria, but at much lower levels than ANP.
  • 配列類似性Belongs to the natriuretic peptide family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ANFB_HUMAN antibody
    • BNP antibody
    • BNP(1-32) antibody
    • BNP(5-29) antibody
    • BNP-32 antibody
    • Brain type natriuretic peptide antibody
    • Gamma brain natriuretic peptide antibody
    • Gamma-brain natriuretic peptide antibody
    • Natriuretic peptide precursor B antibody
    • nppb antibody
    • NT proBNP antibody
    see all

Anti-proBNP antibody [15F11] (ab13115) 使用論文

This product has been referenced in:
  • Tonne JM  et al. Secretion of glycosylated pro-B-type natriuretic peptide from normal cardiomyocytes. Clin Chem 57:864-73 (2011). IP ; Human . Read more (PubMed: 21482747) »

See 1 Publication for this product

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Thank you very much for your inquiry.

I have to confirm that do not have any pro-BNP antibodies that are tested and guaranteed for rat.

I checked the immunogens for the available pro-BNP antibodies and unfortunately I cannot recomme...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"