製品の概要

  • 製品名Anti-PRMT1 antibody
    PRMT1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PRMT1
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding a regio of amino acids 1-100 of Human PRMT 1.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab3769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 40 kDa.
ELISA 1/1000.

ターゲット情報

  • 機能Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Together with dimethylated PIAS1, represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. May be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway.
  • 組織特異性Widely expressed.
  • 配列類似性Belongs to the protein arginine N-methyltransferase family.
  • 細胞内局在Nucleus. Cytoplasm > cytosol.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ANM 1 antibody
    • ANM1 antibody
    • ANM1_HUMAN antibody
    • HCP 1 antibody
    • HCP1 antibody
    • Heterogeneous nuclear ribonucleoprotein methyltransferase 1 like 2 antibody
    • Heterogeneous nuclear ribonucleoproteins methyltransferase like 2 antibody
    • Heterogeneous nuclear ribonucleoproteins methyltransferase like2 antibody
    • Histone-arginine N-methyltransferase PRMT1 antibody
    • HMT 2 antibody
    • HMT1 (hnRNP methyltransferase S. cerevisiae) like 2 antibody
    • HMT1 hnRNP methyltransferase antibody
    • HMT1 hnRNP methyltransferase like 2 (S. cerevisiae) antibody
    • HMT1 hnRNP methyltransferase like 2 antibody
    • HMT2 antibody
    • HRMT1 L2 antibody
    • HRMT1L 2 antibody
    • HRMT1L2 antibody
    • Human mRNA for suppressor for yeast mutant antibody
    • Human mRNA for suppressor for yeast mutant complete cds antibody
    • Interferon receptor 1 bound protein 4 antibody
    • Interferon receptor 1 bound protein4 antibody
    • Interferon receptor 1-bound protein 4 antibody
    • Interferon receptor 1bound protein 4 antibody
    • IR1 B4 antibody
    • IR1B 4 antibody
    • IR1B4 antibody
    • Mrmt 1 antibody
    • Mrmt1 antibody
    • PRMT 1 antibody
    • PRMT1 antibody
    • Protein arginine methyltransferase 1 antibody
    • Protein arginine N methyltransferase 1 antibody
    • Protein arginine N methyltransferase1 antibody
    • Protein arginine N-methyltransferase 1 antibody
    • R1B4 antibody
    • S. cerevisiae like 2 antibody
    see all

Anti-PRMT1 antibody 画像



  • Predicted band size : 40 kDa


    Western blot analysis in whole HL60 cell lysate: PRMT1 (Arrow) was detected using ab3769. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Anti-PRMT1 antibody (ab3769) 使用論文

ab3769 has not yet been referenced specifically in any publications.

Product Wall

I am unable to provide you with both a replacment and positive control. I can issue you a refund - what was the Abcam order number or purchase order number that was used?

Thank you for the details that you have provided us with. I can offer you a replacement vial of ab3769 or a refund. Please let me know which you would prefer.

All the information we have on species cross reactivity is specified on the datasheet. To our knowledge, cross reactivity with Drosophila melanogaster has not yet been tested. Should you decide to go ahead and purchase this product, please let us know...

Read More

The peptide sequence is CGQAESSEKPNAEDMTSK corresponding to the N-term of human PRMT1 (Q99873).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"