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RabMAb

Anti-PRKX 抗体 [EPR4840] (ab109389)

製品の概要

  • 製品名
    Anti-PRKX antibody [EPR4840]
    PRKX 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR4840] to PRKX
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: WB, ICC, Flow Cytmore details
    適用なし: IHC-P or IP
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide within Human PRKX aa 300-400. The exact sequence is proprietary.

  • ポジティブ・コントロール
    • FC: permeabilized A549 cells; WB: A549, Jurkat, 293T, fetal kidney and fetal brain lysates.
  • 特記事項

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファー
    PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 精製度
    Tissue culture supernatant
  • ポリ/モノ
    モノクローナル
  • クローン名
    EPR4840
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab109389 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
ICC 1/100 - 1/250.
Flow Cyt 1/100 - 1/500.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

  • 追加情報
    Is unsuitable for IHC-P or IP.
  • ターゲット情報

    • 組織特異性
      High levels in adult and fetal brain, kidney and lung; low levels in adult placenta, heart, liver, skeletal muscle, pancreas and fetal liver.
    • 関連疾患
      Note=A chromosomal aberration involving PRKX is a cause of sex reversal disorder. Translocation t(X;Y)(p22;p11) with PRKY. Chromosomal translocations proximal to PRKY account for about 30% of the cases of sex reversal disorder in XX males and XY females.
    • 配列類似性
      Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
      Contains 1 AGC-kinase C-terminal domain.
      Contains 1 protein kinase domain.
    • Information by UniProt
    • 参照データベース
    • 別名
      • PKX1 antibody
      • PRKX antibody
      • PRKX_HUMAN antibody
      • Protein kinase PKX1 antibody
      • Serine/threonine-protein kinase PRKX antibody
      see all

    画像

    • All lanes : Anti-PRKX antibody [EPR4840] (ab109389) at 1/1000 dilution

      Lane 1 : A549 cell lysates
      Lane 2 : Jurkat cell lysates
      Lane 3 : 293T cell lysates
      Lane 4 : Human fetal kidney lysates
      Lane 5 : Human fetal brain lysates

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 41 kDa

    参考文献

    This product has been referenced in:
    • Ouyang C  et al. Transforming Growth Factor (TGF)-ß-activated Kinase 1 (TAK1) Activation Requires Phosphorylation of Serine 412 by Protein Kinase A Catalytic Subunit a (PKACa) and X-linked Protein Kinase (PRKX). J Biol Chem 289:24226-37 (2014). WB . Read more (PubMed: 25028512) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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