Anti-PRG2 抗体 [BMK13] (ab14462)


  • 製品名Anti-PRG2 antibody [BMK13]
    PRG2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [BMK13] to PRG2
  • 特異性Specific for eosinophil major basic protein (14kDa) irrespective of the stages of eosinophil activation and can be regarded as a “pan-eosinophil” marker. Recognizes secreted pro-form of MBP (Pregnancy associated MBP, 23.8kDa) and mature form found in the matrix of the eosinophil large specific granule (13.8kDa). The clone number has been updated from (1.B.787) to (BMK13) both clone numbers name the same antibody clone.
  • アプリケーション適用あり: ELISA, IHC-Fr, IHC-P, WBmore details
  • 種交差性
    交差種: Human
    非交差種: Mouse, Rat, Horse
  • 免疫原

    Full length protein (Human).


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 10mM Sodium Azide
    Constituents: 1mg/ml BSA, PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • クローン名BMK13
  • アイソタイプIgG1
  • 研究分野


Our Abpromise guarantee covers the use of ab14462 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
  • 追加情報ELISA: Use at an assay dependent dilution.
    IHC-P: Use at an assay dependent dilution. Perform enzymatic antigen retrieval before commencing with IHC staining protocol (0.1% trypsin).
    IHC-Fr: Use at an assay dependent dilution. Fix with methanol:acetone.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 26.6 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
    • 組織特異性High levels of the proform in placenta and pregnancy serum; in placenta, localized to X cells of septa and anchoring villi. Lower levels in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow and colon.
    • 配列類似性Contains 1 C-type lectin domain.
    • 発生段階Levels of the proform increase in serum and placenta during pregnancy.
    • 翻訳後修飾Nitrated.
    • 細胞内局在Cytoplasmic vesicle > secretory vesicle. The proform is secreted. The mature protein is found in the matrix of the eosinophil's large specific granule and Secreted. The proform is secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BMPG antibody
      • EMBP antibody
      • Eosinophil granule major basic protein antibody
      • Eosinophil major basic protein antibody
      • MBP antibody
      • MBP1 antibody
      • Natural killer cell activator antibody
      • Pregnancy-associated major basic protein antibody
      • PRG 2 antibody
      • PRG2 antibody
      • PRG2_HUMAN antibody
      • Proteoglycan 2 antibody
      • Proteoglycan 2 bone marrow antibody
      • Proteoglycan 2 preproprotein antibody
      see all

    Anti-PRG2 antibody [BMK13] (ab14462) 使用論文

    ab14462 has not yet been referenced specifically in any publications.

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    I have received confirmation from the laboratory that tested ab14462 that your protocol is very good and should work with ab14462. The laboratory shared also the following feedback which may interest you "Your customer's secondary antibody is a She...

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    I have been informed by the source of ab14462 that it was not tested in house in ELISA and that unfortunately we therefore do not know the recommended dilution. I was recommended to start at a concentration of 2-5ug/ml (for Direct or Indirect ELISA), ...

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