製品の概要

  • 製品名Anti-PREX1 antibody
    PREX1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to PREX1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Dog
  • 免疫原

    Synthetic peptide:

    C-ERSNLPTDASTTA

    , corresponding to internal sequence amino acids 1514-1526 of Human PREX1 (NP_065871.2).

  • ポジティブ・コントロール
    • Human temporal cortex lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab99425 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab99425 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 186 kDa.

ターゲット情報

  • 機能Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol-3,4,5-triphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
  • 組織特異性Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues.
  • 配列類似性Contains 1 DEP domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PDZ (DHR) domain.
    Contains 2 PH domains.
  • 細胞内局在Cytoplasm > cytosol. Cell membrane. Mainly cytosolic. Some amount is apparently associated to the plasma membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 4 antibody
    • 5)-dependent Rac exchanger 1 antibody
    • KIAA1415 antibody
    • OTTHUMP00000031228 antibody
    • P REX1 antibody
    • P Rex1 protein like antibody
    • P-Rex1 antibody
    • Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchange factor 1 antibody
    • Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 antibody
    • Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 protein antibody
    • Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein antibody
    • Prex1 antibody
    • PREX1_HUMAN antibody
    • PtdIns(3 antibody
    • PtdIns(3,4,5) dependent Rac exchanger 1 antibody
    • SET domain containing 6 antibody
    • Setd6 antibody
    see all

Anti-PREX1 antibody 画像

  • Anti-PREX1 antibody (ab99425) at 1 µg/ml + Human temporal cortex lysate at 35 µg

    Predicted band size : 186 kDa

Anti-PREX1 antibody (ab99425) 使用論文

ab99425 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab99425.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"