製品の概要

  • 製品名Anti-PRDM6 antibody
    PRDM6 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PRDM6
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 43-72 of Human PRDM6 (NP_001129711.1).

  • ポジティブ・コントロール
    • Jurkat cell line lysates.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab123317 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 64 kDa.

ターゲット情報

  • 機能Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro. 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression.
  • 配列類似性Contains 4 C2H2-type zinc fingers.
    Contains 1 SET domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Gm92 antibody
    • PFM3 antibody
    • PR domain containing 6 antibody
    • PR domain containing protein 6 antibody
    • PR domain zinc finger protein 6 antibody
    • PR domain-containing protein 6 antibody
    • Prdm6 antibody
    • PRDM6_HUMAN antibody
    • PRISM antibody
    • Putative histone-lysine N-methyltransferase PRDM6 antibody
    • RGD1559594 antibody
    see all

Anti-PRDM6 antibody 画像

  • Anti-PRDM6 antibody (ab123317) at 1/100 dilution + Jurkat cell line lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 64 kDa

Anti-PRDM6 antibody (ab123317) 使用論文

ab123317 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab123317.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"