製品の概要

  • 製品名
    Anti-PRDM3 antibody [47AT612.84.88]
  • 製品の詳細
    Mouse monoclonal [47AT612.84.88] to PRDM3
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Fusion protein (GST-tag) corresponding to Human PRDM3 aa 43-208 (N terminal).

  • ポジティブ・コントロール
    • WB: 293 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab3792 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 130 kDa.

ターゲット情報

  • 関連性
    PRDM3 can be produced either as a separate transcript and as a fusion transcript with EVI1. A chromosomal aberration involving PRDM3 is found in a form of acute myeloid leukemia. The myelodysplastic syndromes (MDS, formerly known as "preleukemia") are a diverse collection of hematological conditions united by ineffective production of blood cells and varying risks of transformation to acute myelogenous leukemia.
  • 参照データベース
  • 別名
    • MDS1 antibody
    • MDS1 EVI1 antibody
    • MDS1EVI1 antibody
    • Myelodysplasia syndrome 1 antibody
    • Myelodysplasia syndrome associated protein 1 antibody
    • PRDM 3 antibody
    • PRDM3 antibody
    see all

プロトコール

参考文献

This product has been referenced in:
  • Sgourdou P  et al. Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly. Sci Rep 7:43708 (2017). Read more (PubMed: 28272472) »
  • Jablonski AM  et al. Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance. J Neurosci 35:14286-306 (2015). Read more (PubMed: 26490867) »

See all 3 Publications for this product

レビューと Q&A

Thank you for your enquiry. This antibody was raised using purified recombinant GST fusion protein encoding the 43-208 aa of human PRDM3. I hope this information helps, please do not hesitate to contact us if you need any more advice or information.

It was made against recombinant protein corresponding to the N-term (1-300aa) of human MDS-1 (NM_004991). it should not react with EVI1.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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