製品の概要

  • 製品名
    Anti-PRDM1/Blimp1 antibody
    PRDM1/Blimp1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PRDM1/Blimp1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide, corresponding to a sequence around amino acids 124-128 (

    DTVPK

    ) of Human PRDM1/Blimp1 (NP_001189.2 ).

  • ポジティブ・コントロール
    • Jurkat an Raji cell extracts

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab119401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 95-100 kDa (predicted molecular weight: 93 kDa).

ターゲット情報

  • 機能
    Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569).
  • 配列類似性
    Belongs to the class V-like SAM-binding methyltransferase superfamily.
    Contains 4 C2H2-type zinc fingers.
    Contains 1 SET domain.
  • 翻訳後修飾
    Sumoylation at Lys-816 by PIAS1 augments transcriptional repressor activity, and is critical for plasma cell differentiation.
    Ubiquitinated by the SCF(FBXO11) complex, leading to its degradation by the proteasome.
  • 細胞内局在
    Nucleus. Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • B Lymphocyte Induced Maturation Protein 1 antibody
    • Beta interferon gene positive regulatory domain I binding factor antibody
    • Beta-interferon gene positive regulatory domain I-binding factor antibody
    • BLIMP-1 antibody
    • BLIMP1 antibody
    • Positive Regulatory Domain I Binding Factor 1 antibody
    • Positive regulatory domain I-binding factor 1 antibody
    • PR Domain Containing 1 antibody
    • PR domain containing 1 with ZNF domain antibody
    • PR domain containing 1 with ZNF domain isoform 2 antibody
    • PR domain containing protein 1 antibody
    • PR domain zinc finger protein 1 antibody
    • PR domain-containing protein 1 antibody
    • PRDI BF1 antibody
    • PRDI binding factor 1 antibody
    • PRDI-BF1 antibody
    • PRDI-binding factor 1 antibody
    • PRDM 1 antibody
    • Prdm1 antibody
    • PRDM1_HUMAN antibody
    see all

画像

  • All lanes : Anti-PRDM1/Blimp1 antibody (ab119401) at 1/500 dilution

    Lane 1 : Jurkat cell extract
    Lane 2 : Raji cell extract


    Predicted band size : 93 kDa

プロトコール

参考文献

ab119401 has not yet been referenced specifically in any publications.

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