製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to PRAME
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide from within residues: MVQAWPFTCL PLGVLMKGQH LHLETFKAVL DGLDVLLAQE VRPRRWKLQV , corresponding to N terminal amino acids 72-121 of Human PRAME (NP_006106)

  • ポジティブ・コントロール
    • HepG2 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab90053 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 58 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
  • 組織特異性
    Expressed in testis. Detected in samples of kidney, brain and skin.
  • 配列類似性
    Belongs to the PRAME family.
    Contains 4 LRR (leucine-rich) repeats.
  • 細胞内局在
    Nucleus. Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 4930534P07Rik antibody
    • Cancer/testis antigen 130 antibody
    • CT130 antibody
    • MAPE antibody
    • Melanoma antigen preferentially expressed in tumors antibody
    • OIP 4 antibody
    • OIP-4 antibody
    • OIP4 antibody
    • OPA interacting protein 4 antibody
    • Opa interacting protein OIP4 antibody
    • OPA-interacting protein 4 antibody
    • PRAME antibody
    • PRAME_HUMAN antibody
    • Preferentially expressed antigen in melanoma antibody
    • Preferentially expressed antigen of melanoma antibody
    • RP23-250F8.3 antibody
    see all

画像

  • Anti-PRAME antibody (ab90053) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 58 kDa

プロトコール

参考文献

ab90053 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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