製品の概要

  • 製品名Anti-PPP2R4 antibody
    PPP2R4 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to PPP2R4
  • 特異性This antibody is expected to recognize all reported isoforms (NP_821068.1; NP_066954.2; NP_821070.1).
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
    交差が予測される動物種: Rabbit, Cow, Dog, Orangutan
  • 免疫原

    Synthetic peptide:

    C-GSLLPIHPVTSG

    , corresponding to C terminal amino acids 312-323 of Human PPP2R4 (NP_066954.2).

  • ポジティブ・コントロール
    • Human, mouse or rat Liver lysate and HepG2 cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab87673 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab87673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).

ターゲット情報

  • 機能PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activty of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.
  • 組織特異性Widely expressed.
  • 配列類似性Belongs to the PTPA-type PPIase family.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • subunit B'' antibody
    • KIAA0044 antibody
    • MGC2184 antibody
    • Phosphotyrosyl phosphatase activator antibody
    • PP2A antibody
    • PP2A phosphatase activator antibody
    • PP2A subunit B' antibody
    • PP2A subunit B' isoform PR53 antibody
    • PP2A subunit B' PR53 isoform antibody
    • PPP2R4 antibody
    • PR53 antibody
    • PR53 isoform antibody
    • Protein phosphatase 2, regulatory subunit B-prime antibody
    • Protein phosphatase 2A activator regulatory subunit 4 antibody
    • Protein phosphatase 2A regulatory subunit B' (PR 53) antibody
    • PTPA antibody
    • PTPA_HUMAN antibody
    • Serine/threonine protein phosphatase 2A regulatory subunit B' antibody
    • Serine/threonine-protein phosphatase 2A activator antibody
    • Serine/threonine-protein phosphatase 2A regulatory subunit 4 antibody
    • Serine/threonine-protein phosphatase 2A regulatory subunit B'' antibody
    see all

Anti-PPP2R4 antibody 画像

  • All lanes : Anti-PPP2R4 antibody (ab87673) at 0.5 µg/ml

    Lane 1 : Human Liver lysate in RIPA buffer
    Lane 2 : Mouse Liver lysate in RIPA buffer
    Lane 3 : Rat Liver lysate in RIPA buffer

    Lysates/proteins at 35 µg per lane.

    Developed using the ECL technique

    Predicted band size : 37 kDa
    Observed band size : 37 kDa

Anti-PPP2R4 antibody (ab87673) 使用論文

ab87673 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab87673.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"