製品の概要

  • 製品名Anti-PPP1R3A antibody
    PPP1R3A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PPP1R3A
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide: MEPSEVPSQI SKDNFLEVPN LSDSLCEDEE VTFQPGFSPQ PSRRGSDSSE, corresponding to a region within N terminal amino acids 1-50 of Human PPP1R3A (NP_002702).

  • ポジティブ・コントロール
    • THP1 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab104986 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 126 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.
  • 組織特異性Skeletal muscle and heart.
  • 関連疾患Diabetes mellitus, non-insulin-dependent
  • 配列類似性Contains 1 CBM21 (carbohydrate binding type-21) domain.
  • ドメインThe CBM21 domain is known to be involved in the localization to glycogen and is characteristic of some regulatory subunit of phosphatase complexes.
  • 翻訳後修飾Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle antibody
    • Glycogen associated regulatory subunit of protein phosphatase 1 antibody
    • GM antibody
    • PP1G antibody
    • PPP1R3 antibody
    • PPP1R3A antibody
    • PPR3A_HUMAN antibody
    • Protein phosphatase 1 glycogen-associated regulatory subunit antibody
    • Protein phosphatase 1 glycogen-targeting subunit, muscle antibody
    • Protein phosphatase 1 regulatory subunit 3A antibody
    • Protein phosphatase 1 regulatory subunit GM antibody
    • protein phosphatase 1, regulatory (inhibitor) subunit 3A antibody
    • Protein phosphatase 1, regulatory subunit 3 antibody
    • Protein phosphatase type-1 glycogen targeting subunit antibody
    • RG1 antibody
    • Serine /threonine specific protein phosphatase antibody
    • Type 1 protein phosphatase skeletal muscle glycogen targeting subunit antibody
    see all

Anti-PPP1R3A antibody 画像

  • Anti-PPP1R3A antibody (ab104986) at 1 µg/ml + THP1 cell lysate at 10 µg

    Predicted band size : 126 kDa

Anti-PPP1R3A antibody (ab104986) 使用論文

ab104986 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"