製品の概要

  • 製品名Anti-PPP1A antibody [4G3]
    PPP1A 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [4G3] to PPP1A
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 30-299 of Human PPP1A, purified from E. coli.

  • ポジティブ・コントロール
    • HepG2 cell lysate.
  • 特記事項


    This antibody was derived from the hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab66955 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/2000. Detects a band of approximately 38 kDa (predicted molecular weight: 38 kDa).

Blocking: 5% skim milk in PBS-Tween, for 1hr at room temperature. Incubate overnight.

ELISA Use at an assay dependent concentration.

ターゲット情報

  • 機能Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
  • 配列類似性Belongs to the PPP phosphatase family. PP-1 subfamily.
  • 細胞内局在Cytoplasm. Nucleus. Nucleus > nucleoplasm. Nucleus > nucleolus. Primarily nuclear and largely excluded from the nucleolus. Highly mobile in cells and can be relocalized through interaction with targeting subunits. NOM1 plays a role in targeting this protein to the nucleolus. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Alpha isoform serine threonine protein phosphatase PP1alpha 1 catalytic subunit antibody
    • Catalytic subunit antibody
    • EC 3.1.3.16 antibody
    • MGC15877 antibody
    • MGC1674 antibody
    • PP 1A antibody
    • PP-1A antibody
    • PP1A antibody
    • PP1A_HUMAN antibody
    • PP1alpha antibody
    • PP2C ALPHA antibody
    • PP2CA antibody
    • Ppp1ca antibody
    • Protein Phosphatase 2C Alpha Isoform antibody
    • Serine threonine protein phosphatase PP1 alpha catalytic subunit antibody
    • Serine threonine protein phosphatase PP1 alpha catalytic subunit protein phosphatase 1 antibody
    • Serine/threonine-protein phosphatase PP1-alpha catalytic subunit antibody
    see all

Anti-PPP1A antibody [4G3] 画像

  • Anti-PPP1A antibody [4G3] (ab66955) at 1/1000 dilution + HepG2 cell lysate at 45 µg

    Secondary
    goat anti-mouse
    Developed using the ECL technique

    Predicted band size : 38 kDa
    Observed band size : 38 kDa

Anti-PPP1A antibody [4G3] (ab66955) 使用論文

ab66955 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab66955.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"