製品の概要

  • 製品名Anti-PPM1E antibody
    PPM1E 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PPM1E
  • アプリケーション適用あり: IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    EVEGESLDLC LQQLYKYNCP SFLAAALARA TSDEVLQSDL SAHYIPKETD GTEGTVEIET VKLARSVFSK LHEI internal sequence amino acids 148-221 of Human PPM1E.

  • ポジティブ・コントロール
    • Human cerebellum tissue (Purkinje cells and cells in the molecular layer), Human cell line U-2 OS.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab121571 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Use buffer at pH 6 for antigen retrieval.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100

ターゲット情報

  • 機能Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2 (By similarity). Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42.
  • 配列類似性Belongs to the PP2C family.
    Contains 1 PP2C-like domain.
  • 細胞内局在Nucleus. Cytoplasm. A truncated form, major form, with the C-terminal part missing, is mostly found in the cytoplasm and a little in the nucleus. The full length, minor form, is found in the nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Ca(2+)/calmodulin-dependent protein kinase phosphatase N antibody
    • CaMKN antibody
    • CaMKP-N antibody
    • CaMKP-nucleus antibody
    • KIAA1072 antibody
    • Nuclear calmodulin dependent protein kinase phosphatase antibody
    • Partner of PIX 1 antibody
    • Partner of PIX-alpha antibody
    • Partner of PIXA antibody
    • POPX1 antibody
    • PP2CH antibody
    • Ppm1e antibody
    • PPM1E_HUMAN antibody
    • Protein phosphatase 1E antibody
    • Protein phosphatase Mg2+/Mn2+ dependent 1E antibody
    see all

Anti-PPM1E antibody 画像

  • ab121571, at a 1/10 dilution, staining PPM1E in Purkinje cells and in cells of the molecular layer of paraffin-embedded Human cerebellum tissue by immunohistochemistry.
  • ab121571, at 4 µg/ml, staining PPM1E in the nucleus & nucleoli of PFA/Triton X-100 treated Human cell line U-2 OS by immunofluorescence. Antibody staining is shown in green.

Anti-PPM1E antibody (ab121571) 使用論文

ab121571 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab121571.
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