製品の概要

  • 製品名Anti-PPM1D antibody
    PPM1D 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to PPM1D
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment (GST-tag) corresponding to Human PPM1D aa 496-605.
    Sequence:

    IGLVPTNSTNTVMDQKNLKMSTPGQMKAQEIERTPPTNFKRTLEESNSGP LMKKHRRNGLSRSSGAQPASLPTTSQRKNSVKLTMRRRLRGQKKIGNPLL HQHRKTVCVC


    Database link: O15297

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab56332 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 67 kDa.

ターゲット情報

  • 機能Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins.
  • 配列類似性Belongs to the PP2C family.
    Contains 1 PP2C-like domain.
  • Information by UniProt
  • 参照データベース
  • 別名
    • EC 3.1.3.16 antibody
    • p53 induced protein phosphatase 1 antibody
    • p53-induced protein phosphatase 1 antibody
    • PP2C delta antibody
    • PP2C-delta antibody
    • PP2CD antibody
    • Ppm1d antibody
    • PPM1D_HUMAN antibody
    • Protein phosphatase 1D antibody
    • protein phosphatase 1D magnesium-dependent delta isoform antibody
    • Protein phosphatase 2C delta isoform antibody
    • Protein phosphatase 2C isoform delta antibody
    • Protein phosphatase magnesium dependent 1 delta antibody
    • Protein phosphatase magnesium-dependent 1 delta antibody
    • Protein phosphatase Mg2+/Mn2+ dependent 1D antibody
    • Protein phosphatase Wip1 antibody
    • Wild type p53 induced phosphatase 1 antibody
    • WIP 1 antibody
    • WIP1 antibody
    see all

Anti-PPM1D antibody 画像

  • Anti-PPM1D antibody (ab56332) at 5 µg/ml + 0.2 µg/lane of partial recombinant protein with a tag

    Secondary
    Goat anti mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

    Predicted band size : 67 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-PPM1D antibody (ab56332) at 5 µg/ml

    Lane 1 : 50 µg/lane of transfected 293T cell line lysate
    Lane 2 : 50 µg/lane of non-transfected 293T cell line lysate

    Secondary
    Goat anti mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

    Predicted band size : 67 kDa
    Observed band size : 100 kDa (why is the actual band size different from the predicted?)

Anti-PPM1D antibody (ab56332) 使用論文

ab56332 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab56332.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"