The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 53 kDa.
Use a concentration of 20 µg/ml.
Use at an assay dependent concentration.
機能Involved in epithelial differentiation and contributes to epidermal integrity and barrier formation.
翻訳後修飾Substrate of transglutaminase (in vitro).
細胞内局在Nucleus. Cytoplasm. In undifferentiated keratinocytes expressed in speckle-type nuclear granules and at the nuclear membrane, but in the differentiated keratinocytes colocalized with periplakin at the cell periphery and at cell-cell junctions.