製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to PON2
  • 特異性
    This antibody is expected to recognize isoforms 1 and 2 (NP_000296.2; NP_001018171.1).
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Dog, Pig
  • 免疫原

    Synthetic peptide:

    EKPRARELRIS

    by a Cysteine residue linker, corresponding to internal sequence amino acids 93-103 of Human PON2 (NP_000296.2; NP_001018171.1)

  • ポジティブ・コントロール
    • HepG2 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab99550 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.2 - 0.6 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 39 kDa).

ターゲット情報

  • 機能
    Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.
  • 組織特異性
    Widely expressed with highest expression in liver, lung, placenta, testis and heart.
  • 配列類似性
    Belongs to the paraoxonase family.
  • 翻訳後修飾
    The signal sequence is not cleaved.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • A esterase 2 antibody
    • A-esterase 2 antibody
    • Aromatic esterase 2 antibody
    • Paraoxonase 2 antibody
    • Paraoxonase nirs antibody
    • PON 2 antibody
    • PON2 antibody
    • PON2_HUMAN antibody
    • Serum aryldialkylphosphatase 2 antibody
    • Serum paraoxonase/arylesterase 2 antibody
    see all

Anti-PON2 antibody 画像

  • Anti-PON2 antibody (ab99550) at 1 µg/ml (incubation time 1 hour) + HepG2 cell lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 39 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 60 kDa. We are unsure as to the identity of these extra bands.

プロトコール

Anti-PON2 antibody (ab99550) 使用論文

ab99550 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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