Anti-POLR1C 抗体 - C-terminal (ab82861)

製品の概要

• 製品名
  Anti-POLR1C antibody - C-terminal
  POLR1C 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to POLR1C - C-terminal
• アプリケーション
  適用あり: WB, ELISAmore details
• 種交差性
  交差種: Human
  
• 免疫原

  Synthetic peptide selected from the C terminal region of human POLR1C conjugated to KLH (NP_976035).

• ポジティブ･コントロール
  • A2058 cell line lysates.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• バッファー
  Preservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• 精製度
  Ammonium Sulphate Precipitation
• 特記事項（精製）
  ab82861 is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Epigenetics and Nuclear Signaling
  • Transcription
  • Polymerase associated factors
  • Pol I Transcription

  • Epigenetics and Nuclear Signaling
  • Transcription
  • RNA polymerase

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 機能
  DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
• 関連疾患
  Treacher Collins syndrome 3 (TCS3) [MIM:248390]: A form of Treacher Collins syndrome, a disorder of craniofacial development. Treacher Collins syndrome is characterized by a combination of bilateral downward slanting of the palpebral fissures, colobomas of the lower eyelids with a paucity of eyelashes medial to the defect, hypoplasia of the facial bones, cleft palate, malformation of the external ears, atresia of the external auditory canals, and bilateral conductive hearing loss. Note=The disease is caused by mutations affecting the gene represented in this entry.
• 配列類似性
  Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
• 細胞内局在
  Nucleus.

• Target information above from: UniProt accession O15160 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 9533 Human
  • Omim: 610060 Human
  • SwissProt: O15160 Human
  • Unigene: 584839 Human
• 別名
  • 40kDa antibody
  • AA409007 antibody
  • AA959927 antibody

  • Ac2-127 antibody
  • AC40 antibody
  • AL024089 antibody
  • DNA directed RNA polymerase I subunit C antibody
  • DNA directed RNA polymerases I and III 40 kDa polypeptide antibody
  • DNA directed RNA polymerases I and III subunit RPAC1 antibody
  • DNA-directed RNA polymerase I subunit C antibody
  • DNA-directed RNA polymerases I and III 40 kDa polypeptide antibody
  • DNA-directed RNA polymerases I and III subunit RPAC1 antibody
  • MGC105583 antibody
  • MGC161175 antibody
  • POLR1C antibody
  • POLR1E antibody
  • Polymerase (RNA) I polypeptide C, 30kDa antibody
  • RNA polymerase 1 1 antibody
  • RNA polymerases I and III subunit AC1 antibody
  • RP3-337H4.4 antibody
  • RPA39 antibody
  • RPA40 antibody
  • RPA5 antibody
  • RPAC1 antibody
  • RPAC1_HUMAN antibody
  • RPC40 antibody
  • Rpo1 1 antibody
  • TCS3 antibody

  see all

プロトコール

• Western blot protocols