製品の概要
-
製品名Anti-POLR1C antibody - C-terminal
POLR1C 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to POLR1C - C-terminal
-
由来種Rabbit
-
アプリケーション適用あり: WB, ELISAmore details
-
種交差性交差種: Human
-
免疫原
Synthetic peptide selected from the C terminal region of human POLR1C conjugated to KLH (NP_976035).
-
ポジティブ･コントロール
- A2058 cell line lysates.
製品の特性
-
製品の状態Liquid
-
保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
-
バッファーPreservative: 0.09% Sodium Azide
Constituents: PBS -
Concentration information loading... -
精製度Ammonium Sulphate Precipitation
-
特記事項（精製）ab82861 is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
ポリ/モノポリクローナル
-
アイソタイプIgG
-
研究分野
関連製品
-
Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab82861 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | 1/50 - 1/100. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa). | |
| ELISA | 1/1000. |
ターゲット情報
-
機能DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
-
関連疾患Treacher Collins syndrome 3 (TCS3) [MIM:248390]: A form of Treacher Collins syndrome, a disorder of craniofacial development. Treacher Collins syndrome is characterized by a combination of bilateral downward slanting of the palpebral fissures, colobomas of the lower eyelids with a paucity of eyelashes medial to the defect, hypoplasia of the facial bones, cleft palate, malformation of the external ears, atresia of the external auditory canals, and bilateral conductive hearing loss. Note=The disease is caused by mutations affecting the gene represented in this entry.
-
配列類似性Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
-
細胞内局在Nucleus.
- Information by UniProt
-
参照データベース
- Entrez Gene: 9533 Human
- Omim: 610060 Human
- SwissProt: O15160 Human
- Unigene: 584839 Human
-
別名
- 40kDa antibody
- AA409007 antibody
- AA959927 antibody
see all
画像
-
Western blot - POLR1C antibody - C-terminal (ab82861)Anti-POLR1C antibody - C-terminal (ab82861) at 1/50 dilution + A2058 cell line lysates at 35 µg
Predicted band size: 39 kDa
Observed band size: 39 kDa
プロトコール
参考文献
ab82861 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"