Anti-Polo like kinase kinase (phospho S482 + S486 + S490) 抗体 (ab30565)

製品の概要

  • 製品名Anti-Polo like kinase kinase (phospho S482 + S486 + S490) antibody
  • 製品の詳細
    Rabbit polyclonal to Polo like kinase kinase (phospho S482 + S486 + S490)
  • 特異性Specific for the PLKK protein phosphorylated at serines 482, 486 and 490.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Xenopus laevis
  • 免疫原

    Phosphopeptide corresponding to amino acid residues surrounding the phosphorylation sites Ser 482,486 and 490 of Xenopus polo-like kinase kinase (PLKK).

  • ポジティブ・コントロール
    • Xenopus oocyte lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab30565 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Detects a band of approximately 120 kDa (predicted molecular weight: 112 kDa).

ターゲット情報

  • 関連性Polo-like kinase (PLK) plays an important role in cell cycle regulation. It is required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Recent work led to the identification of a polo-like kinase kinase (PLKK) that is thought to be responsible for activation of PLK. Recent work (Erikson, et al., 2004) has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK.
  • 細胞内局在Nuclear
  • 別名
    • Polo like kinase kinase 1 antibody
    • Serine/threonine kinase 10 antibody
    • stk10 a antibody
    • xPlkk1 antibody

Anti-Polo like kinase kinase (phospho S482 + S486 + S490) antibody (ab30565) 使用論文

ab30565 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab30565.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"