The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: Use at an assay dependent dilution.
Reacts well in ELISA both as catching antibody and as detection antibody. Weak neutralization of Polio Virus type 2 has been observed.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Polio (acute poliomyelitis, infantile paralysis) is caused by the poliovirus, which may infect the nervous system and cause lasting paralysis. Poliovirus is a single stranded RNA virus and a member of the Picornavirus family. It has three strains: Poliovirus 1, 2 and 3. Replication of poliovirus RNA is accomplished by the error prone viral RNA dependent RNA polymerase. The cell receptor for poliovirus is CD155.
This product has been referenced in:
Asati A et al. Fluorescence Adherence Inhibition Assay: A Novel Functional Assessment of Blocking Virus Attachment by Vaccine-Induced Antibodies. PLoS One11:e0144261 (2016).
Read more (PubMed: 26863313) »