製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to Pokemon
  • アプリケーション
    適用あり: WB, IPmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide mapping to a region between 200-250 of human Pokemon.

  • ポジティブ・コントロール
    • HeLa cell lysate.

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab52066 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/2000. Predicted molecular weight: 62 kDa.
IP Use at an assay dependent dilution.

ターゲット情報

  • 機能
    Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.
  • 組織特異性
    Widely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level).
  • 配列類似性
    Contains 1 BTB (POZ) domain.
    Contains 4 C2H2-type zinc fingers.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Factor binding IST protein 1 antibody
    • Factor that binds to inducer of short transcripts protein 1 antibody
    • FBI 1 antibody
    • FBI-1 antibody
    • FBI1 antibody
    • HIV 1 1st binding protein 1 antibody
    • HIV-1 1st-binding protein 1 antibody
    • Leukemia/lymphoma related factor antibody
    • Leukemia/lymphoma-related factor antibody
    • LRF antibody
    • POK erythroid myeloid ontogenic factor antibody
    • Pokemon antibody
    • POZ and Krueppel erythroid myeloid ontogenic factor antibody
    • TIP21 antibody
    • TTF I interacting peptide 21 antibody
    • TTF-I-interacting peptide 21 antibody
    • ZBT7A_HUMAN antibody
    • ZBTB7 antibody
    • ZBTB7A antibody
    • Zinc finger and BTB domain containing protein 7A antibody
    • Zinc finger and BTB domain-containing protein 7A antibody
    • Zinc finger protein 857A antibody
    see all

参考文献

ab52066 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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