製品の概要

  • 製品名Anti-PNPO antibody [1H9]
    PNPO 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [1H9] to PNPO
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein of human PNPO produced in HEK293T cells (NP_060599).

  • ポジティブ・コントロール
    • HEK293T cells transfected with PNPO, Human breast, Human Kidney, Carcinoma of Human liver, and Human thyroid tissues
  • 特記事項Dilute in PBS (pH7.3) before use.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab119395 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500. Predicted molecular weight: 30 kDa.
IHC-P 1/150.

ターゲット情報

  • 機能Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
  • パスウェイCofactor biosynthesis; B6 vitamer interconversion; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.
    Cofactor biosynthesis; B6 vitamer interconversion; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.
  • 関連疾患Defects in PNPO are the cause of pyridoxine-5'-phosphate oxidase deficiency (PNPO deficiency) [MIM:610090]; also known as PNPO-related neonatal epileptic encephalopathy. The main feature of neonatal epileptic encephalopathy is the onset within hours of birth of a severe seizure disorder that does not respond to anticonvulsant drugs and can be fatal. Seizures can cease with the administration of PLP, being resistant to treatment with pyridoxine.
  • 配列類似性Belongs to the pyridoxamine 5'-phosphate oxidase family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • EC 1.4.3.5 antibody
    • FLJ10535 antibody
    • PDXPO antibody
    • PNPO antibody
    • PNPO_HUMAN antibody
    • Pyridoxal 5' phosphate synthase antibody
    • pyridoxamine 5' phosphate oxidase antibody
    • Pyridoxamine phosphate oxidase antibody
    • Pyridoxamine-phosphate oxidase antibody
    • pyridoxine 5' phosphate oxidase antibody
    • Pyridoxine-5'-phosphate oxidase antibody
    see all

Anti-PNPO antibody [1H9] 画像

  • All lanes : Anti-PNPO antibody [1H9] (ab119395) at 1/500 dilution

    Lane 1 : HEK293T cell lysate transfected with the pCMV6-ENTRY control
    Lane 2 : HEK293T cell lysate transfected with the pCMV6-ENTRY PNPO

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 30 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC200133)
  • Immunohistochemical staining of paraffin-embedded Human breast tissue using ab119395 at a dilution of 1/150.
  • Immunohistochemical staining of paraffin-embedded Human Kidney tissue using ab119395 at a dilution of 1/150.
  • Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using ab119395 at a dilution of 1/150.
  • Immunohistochemical staining of paraffin-embedded Human thyroid tissue using ab119395 at a dilution of 1/150.

Anti-PNPO antibody [1H9] (ab119395) 使用論文

ab119395 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"