製品の概要

  • 製品名Anti-PMM2 antibody
    PMM2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PMM2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow
  • 免疫原

    Recombinant fragment, corresponding to amino acids 1-184 of Human PMM2.

  • ポジティブ・コントロール
    • HeLa and HepG2 whole cell lysates; 293T cell lysate.

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab96399 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 28 kDa.

ターゲット情報

  • 機能Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
  • パスウェイNucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.
  • 関連疾患Defects in PMM2 are the cause of congenital disorder of glycosylation type 1A (CDG1A) [MIM:212065]; also known as carbohydrate-deficient glycoprotein syndrome type Ia (CDGS1A) or Jaeken syndrome. Congenital disorders of glycosylation are metabolic deficiencies in glycoprotein biosynthesis that usually cause severe mental and psychomotor retardation. They are characterized by under-glycosylated serum glycoproteins. CDG1A is an autosomal recessive disorder characterized by a severe encephalopathy with axial hypotonia, abnormal eye movement, and pronounced psychomotor retardation, as well as peripheral neuropathy, cerebellar hypoplasia, and retinitis pigmentosa. Patients show a peculiar distribution of subcutaneous fat, nipple retraction, and hypogonadism.
  • 配列類似性Belongs to the eukaryotic PMM family.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AI585868 antibody
    • BOS_22465 antibody
    • C86848 antibody
    • CDG 1 antibody
    • CDG1 antibody
    • CDG1a antibody
    • CDGS antibody
    • MGC127449 antibody
    • Phosphomannomutase 2 antibody
    • PMM 2 antibody
    • Pmm2 antibody
    • PMM2_HUMAN antibody
    see all

Anti-PMM2 antibody 画像

  • All lanes : Anti-PMM2 antibody (ab96399) at 1/1000 dilution

    Lane 1 : HeLa whole cell lysate
    Lane 2 : HepG2 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 28 kDa

Anti-PMM2 antibody (ab96399) 使用論文

ab96399 has not yet been referenced specifically in any publications.

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