製品の概要

  • 製品名
    (±)-Clopidogrel sulfate
  • 製品の詳細
    Potent, selective P2Y12 antagonist
  • 生理活性の詳細
    Potent, selective P2Y12 antagonist. Potent antithrombotic drug that inhibits ADP-induced platelet aggregation. Clopidogrel is not active in vitro and is the precursor to an active metabolite formed in the liver.
  • 精製度
    > 99%

製品の特性

  • 体系名
    Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate hydrogensulfate
  • 分子量
    419.89
  • 構造式
    Chemical Structure
  • 分子式
    C16H16ClNO2S.H2SO4
  • CAS 番号
    135046-48-9
  • 保存方法
    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • 溶解性
    Soluble in DMSO to 10 mM and in ethanol to 100 mM (with heating)
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES 線形表記
    O=S(O)OO.Clc1ccccc1C(N2CCc3sccc3C2)C(=O)OC
  • 由来

    Synthetic

  • 研究分野

参考文献

This product has been referenced in:
  • Savi P & Herbert JM Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin Thromb Hemost 31:174-83 (2005). Read more (PubMed: 15852221) »
  • Herbert JM & Savi P P2Y12, a new platelet ADP receptor, target of clopidogrel. Semin Vasc Med 3:113-22 (2003). Read more (PubMed: 15199474) »
  • Savi P  et al. Identification and biological activity of the active metabolite of clopidogrel. Thromb Haemost 84:891-6 (2000). Read more (PubMed: 11127873) »

See 0 Publications for this product

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