製品の概要

  • 製品名(±)-BAYK8644
  • 製品の詳細
    Potent L-type Ca2+ channel activator
  • 生理活性の詳細Potent L-type Ca2+ channel activator (EC50 = 17.3 nM). Centrally active following systemic administration.
  • 精製度> 99%

製品の特性

  • 体系名1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester
  • 分子量356.30
  • 構造式Chemical Structure
  • 分子式C16H15F3N2O4
  • CAS 番号71145-03-4
  • 保存方法Store at +4°C. Store under Desiccating conditions. The product can be stored for up to 12 months.
  • 溶解性Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • 由来

    Synthetic

  • 研究分野

    (±)-BAYK8644 (ab120366) 使用論文

    This product has been referenced in:
    • Samantaray S  et al. Calcium channel agonist, (+/-)-Bay K8644, causes a transient increase in striatal monoamine oxidase activity in Balb/c mice. Neurosci Lett 342:73-6 (2003). Read more (PubMed: 12727321) »
    • Bourson A  et al. Central and peripheral effects of the dihydropyridine calcium channel activator BAY K 8644 in the rat. Eur J Pharmacol 160:339-47 (1989). Read more (PubMed: 2469593) »
    • Rae GA & Calixto JB Interactions of calcium antagonists and the calcium channel agonist Bay K 8644 on neurotransmission of the mouse isolated vas deferens. Br J Pharmacol 96:333-40 (1989). Read more (PubMed: 2466518) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"