製品の概要

  • 製品名Anti-PLOD3 antibody
    PLOD3 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to PLOD3
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Human PLOD3 (NP_001075.1)

  • ポジティブ・コントロール
    • HepG2 cell lysate, PLOD3 transfected 293T cell lysate and HeLa cell

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab89263 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ICC/IF
  • 追加情報ICC/IF: Use at a concentration of 10 µg/ml.
    WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 85 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
    • 関連疾患Defects in PLOD3 are the cause of lysyl hydroxylase 3 deficiency (LH3 deficiency) [MIM:612394]; also known as bone fragility with contractures arterial rupture and deafness. LH3 deficiency is a connective tissue disorder. The syndrome is characterized by congenital malformations severely affecting many tissues and organs and revealing features of several collagen disorders, most of them involving COL2A1 (type II collagen). The findings suggest that the failure of lysyl hydroxylation and hydroxylysyl carbohydrate addition, which affects many collagens, is the molecular basis of this syndrome.
    • 配列類似性Contains 1 Fe2OG dioxygenase domain.
    • 細胞内局在Rough endoplasmic reticulum membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 2-oxoglutarate 5-dioxygenase 3 antibody
      • bone protein I antibody
      • BP-I antibody
      • LH3 antibody
      • Lysine hydroxylase 3 antibody
      • Lysyl hydroxylase 3 antibody
      • Plod3 antibody
      • PLOD3_HUMAN antibody
      • Procollagen lysine,2 oxoglutarate 5 dioxygenase 3 precursor antibody
      • Procollagen-lysine antibody
      see all

    Anti-PLOD3 antibody 画像

    • Anti-PLOD3 antibody (ab89263) at 5 µg/ml + HepG2 cel lysate at 50 µg

      Predicted band size : 85 kDa
    • All lanes : Anti-PLOD3 antibody (ab89263) at 5 µg/ml

      Lane 1 : PLOD3 transfected 293T cell lysate
      Lane 2 : Non-transfected lysate

      Lysates/proteins at 50 µg per lane.


      Predicted band size : 85 kDa
    • ab89263 at 10µg/ml staining PLOD3 on HeLa cell by immunofluorescence

    Anti-PLOD3 antibody (ab89263) 使用論文

    ab89263 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab89263.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"