製品の概要

  • 製品名Anti-PLGF antibody [RM0010-8F09]
    PLGF 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [RM0010-8F09] to PLGF
  • 特異性ab51654 recognizes mouse PLGF.
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Recombinant full length protein (Mouse)

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab51654 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/50 - 1/100.
WB 1/400 - 1/1000. Predicted molecular weight: 25 kDa.

ターゲット情報

  • 機能Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner.
  • 組織特異性While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas.
  • 配列類似性Belongs to the PDGF/VEGF growth factor family.
  • ドメインIsoform PlGF-2 contains a basic insert which acts as a cell retention signal.
  • 翻訳後修飾N-glycosylated.
  • 細胞内局在Secreted. The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.
  • Information by UniProt
  • 参照データベース
  • 別名
    • D12S1900 antibody
    • Pgf antibody
    • PGFL antibody
    • PIGF antibody
    • Placenta growth factor antibody
    • Placental growth factor antibody
    • Placental growth factor, vascular endothelial growth factor related protein antibody
    • PlGF 2 antibody
    • PlGF antibody
    • PLGF_HUMAN antibody
    • PlGF2 antibody
    • SHGC 10760 antibody
    see all

Anti-PLGF antibody [RM0010-8F09] 画像

  • ab51654 at 1/100 dilution, staining PLGF in LPS exposed mouse lung tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections).

Anti-PLGF antibody [RM0010-8F09] (ab51654) 使用論文

This product has been referenced in:
  • Li Y  et al. Folate Deficiency Could Restrain Decidual Angiogenesis in Pregnant Mice. Nutrients 7:6425-45 (2015). WB ; Mouse . Read more (PubMed: 26247969) »
  • Saad AF  et al. Effects of pravastatin on angiogenic and placental hypoxic imbalance in a mouse model of preeclampsia. Reprod Sci 21:138-45 (2014). Mouse . Read more (PubMed: 23749761) »

See all 3 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab51654.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"