製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to PLGF
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Pig
  • 免疫原

    Synthetic peptide:

    NVTMQLLKIRSGDR

    by a Cysteine residue linker, corresponding to internal sequence amino acids 101-114 of Human PLGF (NP_002623.2)

  • ポジティブ・コントロール
    • Human Placenta lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab99250 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 25 kDa).

ターゲット情報

  • 機能
    Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner.
  • 組織特異性
    While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas.
  • 配列類似性
    Belongs to the PDGF/VEGF growth factor family.
  • ドメイン
    Isoform PlGF-2 contains a basic insert which acts as a cell retention signal.
  • 翻訳後修飾
    N-glycosylated.
  • 細胞内局在
    Secreted. The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.
  • Information by UniProt
  • 参照データベース
  • 別名
    • D12S1900 antibody
    • Pgf antibody
    • PGFL antibody
    • PIGF antibody
    • Placenta growth factor antibody
    • Placental growth factor antibody
    • Placental growth factor, vascular endothelial growth factor related protein antibody
    • PlGF 2 antibody
    • PlGF antibody
    • PLGF_HUMAN antibody
    • PlGF2 antibody
    • SHGC 10760 antibody
    see all

Anti-PLGF antibody 画像

プロトコール

Anti-PLGF antibody (ab99250) 使用論文

This product has been referenced in:
  • Ott CJ  et al. Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus. Proc Natl Acad Sci U S A 106:19934-9 (2009). Read more (PubMed: 19897727) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab99250.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録