Anti-PLCG 2 (phospho Y753) 抗体 (ab55273)

製品の概要

  • 製品名
    Anti-PLCG 2 (phospho Y753) antibody
    PLCG 2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PLCG 2 (phospho Y753)
  • 特異性
    ab55273 detects endogenous levels of PLCG2 only when phosphorylated at tyrosine 753.
  • アプリケーション
    適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic phosphopeptide derived from human PLCG2 around the phosphorylation site of tyrosine 753 (S-L-YP-D-V).

  • ポジティブ・コントロール
    • human breast carcinoma tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab55273 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/5000.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • 機能
    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
  • 配列類似性
    Contains 1 C2 domain.
    Contains 1 PH domain.
    Contains 1 PI-PLC X-box domain.
    Contains 1 PI-PLC Y-box domain.
    Contains 2 SH2 domains.
    Contains 1 SH3 domain.
  • 翻訳後修飾
    Phosphorylated on tyrosine residues; upon ligand-induced activation of a variety of growth factor receptors and immune system receptors. Increases phospholipase activity.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2 antibody
    • 1-phosphatidylinositol-4 antibody
    • 5-bisphosphate phosphodiesterase gamma-2 antibody
    • EC 3.1.4.11 antibody
    • Phosphoinositide phospholipase C antibody
    • Phosphoinositide phospholipase C-gamma-2 antibody
    • Phospholipase C gamma 2 antibody
    • Phospholipase C, gamma 2 (phosphatidylinositol specific) antibody
    • Phospholipase C-gamma-2 antibody
    • Phospholipase C-IV antibody
    • PLC 2 antibody
    • PLC gamma 2 antibody
    • PLC IV antibody
    • PLC-gamma-2 antibody
    • PLC-IV antibody
    • Plcg2 antibody
    • PLCG2_HUMAN antibody
    see all

画像

  • Immunohistochemical analysis of PLCG 2 (phospho Y753) expression in paraffin embedded human breast carcinoma tissue using 1/50 ab55273. Left: untreated sample. Right: sample treated with immunising phosphopeptide.

プロトコール

参考文献

ab55273 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab55273.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録