製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to PLC-delta-3
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to N terminal amino acids 59-89 of Human PLC-delta-3 (NP_588614.1).

  • ポジティブ・コントロール
    • Mouse liver tissue lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab123668 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 89 kDa.

ターゲット情報

  • 機能
    Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow.
  • 組織特異性
    Present in corneal epithelial cells (at protein level).
  • 配列類似性
    Contains 1 C2 domain.
    Contains 3 EF-hand domains.
    Contains 1 PH domain.
    Contains 1 PI-PLC X-box domain.
    Contains 1 PI-PLC Y-box domain.
  • ドメイン
    The C2 domain is a Ca(2+)-dependent membrane-targeting module.
    The PH domain mediates interaction with the surface membrane by binding to PIP2.
  • 細胞内局在
    Membrane. Cytoplasm. Cleavage furrow. Localizes at the cleavage furrow during cytokinesis.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 1-phosphatidylinositol-4 antibody
    • 5-bisphosphate phosphodiesterase delta-3 antibody
    • Phosphoinositide phospholipase C-delta-3 antibody
    • Phospholipase C-delta-3 antibody
    • PLC-delta-3 antibody
    • PLCD3 antibody
    • PLCD3_HUMAN antibody
    see all

Anti-PLC-delta-3 antibody 画像

  • Anti-PLC-delta-3 antibody (ab123668) at 1/100 dilution + Mouse liver tissue lysates at 35 µg

    Predicted band size : 89 kDa

プロトコール

Anti-PLC-delta-3 antibody (ab123668) 使用論文

ab123668 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab123668.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録