Anti-Plasma Kallikrein 1B 抗体 (ab116517)

製品の概要

  • 製品名Anti-Plasma Kallikrein 1B antibody
    Plasma Kallikrein 1B 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Plasma Kallikrein 1B
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 507-537 of Human Plasma Kallikrein 1B (NP_000883.2).

  • ポジティブ・コントロール
    • K562 cell line lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファーPreservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab116517 is purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab116517 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 71 kDa.

ターゲット情報

  • 機能The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
  • 関連疾患Defects in KLKB1 are the cause of prekallikrein deficiency (PKK deficiency) [MIM:612423]; also known as Fletcher factor deficiency. This disorder is a blood coagulation defect.
  • 配列類似性Belongs to the peptidase S1 family. Plasma kallikrein subfamily.
    Contains 4 apple domains.
    Contains 1 peptidase S1 domain.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Fletcher factor antibody
    • kallikrein B plasma antibody
    • Kallikrein B plasma (Fletcher factor) 1 antibody
    • Kallikrein B, plasma 1 antibody
    • Kininogenin antibody
    • KLK3 antibody
    • KLKB1 antibody
    • KLKB1_HUMAN antibody
    • Plasma kallikrein antibody
    • Plasma kallikrein B1 antibody
    • Plasma kallikrein light chain antibody
    • Plasma prekallikrein antibody
    • PPK antibody
    • Prekallikrein antibody
    see all

Anti-Plasma Kallikrein 1B antibody 画像

  • Anti-Plasma Kallikrein 1B antibody (ab116517) at 1/100 dilution + K562 cell line lysate at 35 µg

    Predicted band size : 71 kDa

Anti-Plasma Kallikrein 1B antibody (ab116517) 使用論文

ab116517 has not yet been referenced specifically in any publications.

Product Wall

Following up my previous message, the immunogen for ab116517 is in fact contained within the light chain sequence. (I asked for the homology to be checked using the sequence below, UniProt P14272 aa 391-638).

IVGGTNSSLGEWPWQVSLQVKLVSQNHMCGGS...

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The alignment of the immunogen for ab116517, Anti-Plasma Kallikrein 1B antibody, with the rat protein gives the following:

Identities = 11/15 (73%), Positives = 12/15 (80%), Gaps = 0/15 (0%)

The lab neglected to tell me whether th...

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I will send the alignment results for ab116517, hopefully later today.

I am glad ab1006 is working, at least with human samples. If you have time, we encourage our customers to send us reviews of their results, positive or negative, via our ...

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This is frustrating for us too, finding incorrect information on our datasheets. We try to minimize it but there is clearly work to be done.

I did not realize you had already purchased the antibody. If you would still like to try it with rat...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"