組織特異性Found in desmosomes of most simple and stratified epithelia. Not found in foreskin fibroblasts and various sarcoma-derived cell lines. Beside dendritic reticular cells of lymphatic follicles not found in non-epithelial desmosome-bearing tissues.
配列類似性Belongs to the beta-catenin family. Contains 8 ARM repeats.
細胞内局在Nucleus. Cell junction > desmosome. Nuclear and associated with desmosomes.