Anti-PKC epsilon 抗体 [17] (ab11724)

製品の概要

  • 製品名Anti-PKC epsilon antibody [17]
    PKC epsilon 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [17] to PKC epsilon
  • 特異性ab11724 recognises the epsilon isoform of protein kinase C. This antibody recognises the sequence NQEEFKGFSYFGEDLMP at the C terminus of PKC epsilon.
  • アプリケーション適用あり: IHC-Fr, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    C-terminal peptide of human PKC epsilon.

  • 特記事項This product should be stored undiluted. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.


    This is a calcium-independent, phospholipid-dependent enzyme specific for serine and threonine. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumour promoters.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: Tissue Culture Supernatant
  • 精製度Tissue culture supernatant
  • 一次抗体 備考This is a calcium-independent, phospholipid-dependent enzyme specific for serine and threonine. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumour promoters.
  • ポリ/モノモノクローナル
  • クローン名17
  • ミエローマSp2/0
  • アイソタイプIgG2a
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab11724 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr 1/10.
WB 1/10 - 1/500. Predicted molecular weight: 88.4 kDa.

ターゲット情報

  • 機能This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.
    PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
  • 配列類似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 C2 domain.
    Contains 2 phorbol-ester/DAG-type zinc fingers.
    Contains 1 protein kinase domain.
  • ドメインThe C1 domain, containing the phorbol ester/DAG-type region 1 (C1A) and 2 (C1B), is the diacylglycerol sensor and the C2 domain is a non-calcium binding domain.
  • 翻訳後修飾Phosphorylation on Thr-566 by PDPK1 triggers autophosphorylation on Ser-729.
  • Information by UniProt
  • 参照データベース
  • 別名
    • KPCE_HUMAN antibody
    • MGC125656 antibody
    • MGC125657 antibody
    • nPKC epsilon antibody
    • nPKC-epsilon antibody
    • PKCE antibody
    • Pkcea antibody
    • PRKCE antibody
    • Protein kinase C epsilon antibody
    • Protein kinase C epsilon type antibody
    see all

Anti-PKC epsilon antibody [17] (ab11724) 使用論文

ab11724 has not yet been referenced specifically in any publications.

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Thank you for your enquiry. I am sorry but we do not recommend a positive control lysate for this antibody. However, following some literature searching I have found a publication where a purified form of the protein was used to demonstrate express...

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Thank you for your e-mail regarding the antibody ab11724. I appreciate you taking the time to express your disappointment with this product, your opinion is very valuable to us and we take your comments very seriously. Thank you for the images which al...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"